Early mortality in acute promyelocytic leukemia: Potential predictors

  title={Early mortality in acute promyelocytic leukemia: Potential predictors},
  author={Can Chen and Xilian Huang and Kaile Wang and Kuang Kuo Chen and Danquan Gao and Shenxian Qian},
  booktitle={Oncology letters},
Acute promyelocytic leukemia (APL) is a rare leukemia characterized by the balanced reciprocal translocation between the promyelocytic leukemia gene on chromosome 15 and the retinoic acid receptor α (RARα) gene on chromosome 17, and accounts for 10-15% of newly diagnosed acute myeloid leukemia each year. The combined use of all-trans retinoic acid and arsenic trioxide (ATO) as primary therapy has markedly improved the survival rate of patients with APL. Mortality in the first 30 days following… CONTINUE READING


Publications referenced by this paper.

AC and Assumpcão JG: Correlation between FLT3‐ITD status and clinical, cellular and molecular profiles in promyelocytic acute leukemias

  • CP Souza Melo, CB Campos, +6 authors Ferreira
  • Leuk Res
  • 2015
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