Early-life stress affects extinction during critical periods of development: an analysis of the effects of maternal separation on extinction in adolescent rats.

@article{Callaghan2012EarlylifeSA,
  title={Early-life stress affects extinction during critical periods of development: an analysis of the effects of maternal separation on extinction in adolescent rats.},
  author={Bridget L. Callaghan and Rick Richardson},
  journal={Stress},
  year={2012},
  volume={15 6},
  pages={671-9}
}
Adolescence is a period of heightened susceptibility to anxiety disorders, yet we have little experimental evidence on what factors may lead to psychopathology in adolescence. Preclinical models of extinction are commonly used to study the treatment of anxiety symptoms. Interestingly, recent research has shown that there are fundamental changes in the process of extinction across development, which may have implications for our understanding of psychopathology across the lifespan. Specifically… CONTINUE READING
12 Citations
41 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 41 references

Compensation in the neural circuitry of fear conditioning awakens learning circuits in the bed nuclei of the stria terminalis

  • AM Poulos, R Ponnusamy, Dong H-W, Fanselow MS.
  • Proc Natl Acad Sci USA 107:14881–14886.
  • 2010
1 Excerpt

Similar Papers

Loading similar papers…