Early life nutrition modulates muscle stem cell number: implications for muscle mass and repair.

@article{Woo2011EarlyLN,
  title={Early life nutrition modulates muscle stem cell number: implications for muscle mass and repair.},
  author={Melissa Woo and Elvira Isganaitis and Massimiliano Cerletti and Connor Fitzpatrick and Amy J. Wagers and Jos{\'e} C Jimenez-Chillaron and Mary Elizabeth Patti},
  journal={Stem cells and development},
  year={2011},
  volume={20 10},
  pages={1763-9}
}
Suboptimal nutrition during prenatal and early postnatal development is associated with increased risk for type 2 diabetes during adult life. A hallmark of such diabetes risk is altered body composition, including reduced lean mass and increased adiposity. Since stem cell number and activity are important determinants of muscle mass, modulation of perinatal nutrition could alter stem cell number/function, potentially mediating developmentally programmed reductions in muscle mass. Skeletal… CONTINUE READING

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High glucose induces adipogenic differentiation of muscle-derived stem cells.

Proceedings of the National Academy of Sciences of the United States of America • 2008
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