Early left ventricular dysfunction elicits activation of sympathetic drive and attenuation of parasympathetic tone in the paced canine model of congestive heart failure.

@article{Eaton1995EarlyLV,
  title={Early left ventricular dysfunction elicits activation of sympathetic drive and attenuation of parasympathetic tone in the paced canine model of congestive heart failure.},
  author={Gregory M Eaton and Robert J. Cody and Eleonora Nunziata and Philip F. Binkley},
  journal={Circulation},
  year={1995},
  volume={92 3},
  pages={555-61}
}
BACKGROUND Although autonomic imbalance is known to be characteristics of patients with clinically overt symptomatic congestive heart failure, it is currently unknown whether this autonomic response arises early in the course of left ventricular dysfunction or is restricted to the later stages of circulatory failure. METHODS AND RESULTS This investigation utilized the technique of spectral analysis of heart rate variability in a paced canine model of congestive heart failure that permits an… CONTINUE READING

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