Early influences on human energy regulation: thrifty genotypes and thrifty phenotypes.

@article{Prentice2005EarlyIO,
  title={Early influences on human energy regulation: thrifty genotypes and thrifty phenotypes.},
  author={Andrew M Prentice},
  journal={Physiology & behavior},
  year={2005},
  volume={86 5},
  pages={640-5}
}
Early influences on human ingestive behavior and other aspects of energy homeostasis can be defined according to two very different time scales: the evolutionary time frame responsible for selection of behavioral and metabolic traits embedded within the genome; and the life-course time frame responsible for setting the phenotype. Evolutionary influences: Famine has been a constant threat to human survival leading to the selection of thrifty genes. Thriftiness can take many forms: metabolic (an… CONTINUE READING