Early infection and spread of a conditionally replicating adenovirus under conditions of plaque formation.

Abstract

Conditionally-replicating adenoviruses (CRAds) and other oncolytic viruses replicate selectively in tumor cells, presenting a potential cancer treatment approach. To optimize application of these viruses, understanding of early spread of these viruses in target cells is important. Here we used a recombinant adenovirus expressing enhanced jellyfish green… (More)
DOI: 10.1016/j.virol.2011.11.014

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