Early hospital discharge of children with cancer treated for fever and neutropenia: identification and management of the low-risk patient.

@article{Mullen1990EarlyHD,
  title={Early hospital discharge of children with cancer treated for fever and neutropenia: identification and management of the low-risk patient.},
  author={Craig A. Mullen and George R. Buchanan},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={1990},
  volume={8 12},
  pages={1998-2004}
}
Children with leukemia and solid tumors are often hospitalized for empiric broad-spectrum antibiotic therapy because of fever during periods of chemotherapy-induced neutropenia. Conventional practice dictates that parenteral antibiotics be continued until the patient is afebrile and has recovered from neutropenia, ie, until the absolute neutrophil count (ANC) exceeds 500 cells per cubic millimeter. However, the practice in our center has been to discontinue parenteral antibiotic therapy and… CONTINUE READING