Early growth response transcription factors and the modulation of immune response: implications towards autoimmunity.

@article{GmezMartn2010EarlyGR,
  title={Early growth response transcription factors and the modulation of immune response: implications towards autoimmunity.},
  author={Diana G{\'o}mez-Mart{\'i}n and Mariana D{\'i}az-Zamudio and Miguel A. Galindo-Campos and Jorge Alcocer-Varela},
  journal={Autoimmunity reviews},
  year={2010},
  volume={9 6},
  pages={
          454-8
        }
}
Early Growth Response (EGR) zinc finger transcription factors are induced under diverse mitogenic signals on different cell types such as lymphocytes. Their genetic expression does not require de novo protein synthesis, which suggests its role as immediate response mediators between cell surface receptor signaling and gene expression regulation. EGR factors are involved in modulating the immune response, by means of the induction of differentiation of lymphocyte precursors, activation of T and… CONTINUE READING
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