Early growth response protein 1 upregulation and nuclear translocation by 2'-benzoyloxycinnamaldehyde induces prostate cancer cell death.

Abstract

2'-Benzoyloxycinnamaldehyde (BCA) induces apoptosis in human cancer cells through ROS generation. BCA upregulates proapoptotic genes such as activating transcription factor 3 (ATF3), NSAID-activated gene 1 protein (NAG-1), and growth arrest and DNA-damage-inducible protein alpha (GADD45A) in prostate cancer cells. These genes are known to be induced by… (More)
DOI: 10.1016/j.canlet.2012.11.006

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Cite this paper

@article{Kang2013EarlyGR, title={Early growth response protein 1 upregulation and nuclear translocation by 2'-benzoyloxycinnamaldehyde induces prostate cancer cell death.}, author={Hye-Sook Kang and Jiyeon Ock and Heon-Jin Lee and Yu-Jin Lee and Byoung-Mog Kwon and Su-Hyung Hong}, journal={Cancer letters}, year={2013}, volume={329 2}, pages={217-27} }