Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats.

@article{SassyPrigent2000EarlyGM,
  title={Early glomerular macrophage recruitment in streptozotocin-induced diabetic rats.},
  author={C Sassy-Prigent and Didier Heudes and Chantal Mandet and Marie France Belair and Odile Michel and B. Perdereau and Jean Bari{\'e}ty and Patrick Bruneval},
  journal={Diabetes},
  year={2000},
  volume={49 3},
  pages={466-75}
}
Diabetic glomerulosclerosis is defined by increased glomerular extracellular matrix (ECM) that is mainly synthesized by mesangial cells that underwent an activation mediated by cytokines and growth factors from various cellular origins. In this study, we tested whether macrophages could infiltrate the glomeruli and influence ECM synthesis in experimental diabetes. To test our hypothesis, we initially studied the dynamics of glomerular macrophage recruitment in streptozotocin-induced diabetic… CONTINUE READING

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Macrophages in renal injury.

American journal of kidney diseases : the official journal of the National Kidney Foundation • 1998

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