Early glial cell reactivity in experimental retinal detachment: effect of suramin.

@article{Uhlmann2003EarlyGC,
  title={Early glial cell reactivity in experimental retinal detachment: effect of suramin.},
  author={Susann Uhlmann and Andreas Bringmann and Ortrud Uckermann and Thomas Pannicke and Michael Weick and Elke Ulbricht and Iwona Goczalik and Andreas Reichenbach and Peter Wiedemann and Mike Francke},
  journal={Investigative ophthalmology \& visual science},
  year={2003},
  volume={44 9},
  pages={
          4114-22
        }
}
PURPOSE In a rabbit model of retinal detachment, early Müller glial cell reactivity was monitored-specifically, changes in membrane features-to determine whether these changes involve an upregulation of purinergic P2 receptor-mediated responses and whether all or some of these alterations could be blocked by suramin or pyridoxal phosphate 6-azophenyl-2',4'-disulfonic acid (PPADS). In addition, the immune cell reactivity (microglial cells and blood-derived immune cells) was monitored. METHODS… 

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