Early frontotemporal dementia targets neurons unique to apes and humans.

@article{Seeley2006EarlyFD,
  title={Early frontotemporal dementia targets neurons unique to apes and humans.},
  author={William W. Seeley and Danielle A Carlin and John M. Allman and Marcelo N Macedo and Clarissa Bush and Bruce L. Miller and Stephen J. DeArmond},
  journal={Annals of neurology},
  year={2006},
  volume={60 6},
  pages={660-7}
}
OBJECTIVE Frontotemporal dementia (FTD) is a neurodegenerative disease that erodes uniquely human aspects of social behavior and emotion. The illness features a characteristic pattern of early injury to anterior cingulate and frontoinsular cortex. These regions, though often considered ancient in phylogeny, are the exclusive homes to the von Economo neuron (VEN), a large bipolar projection neuron found only in great apes and humans. Despite progress toward understanding the genetic and… CONTINUE READING
Related Discussions
This paper has been referenced on Twitter 3 times. VIEW TWEETS

Citations

Publications citing this paper.
Showing 1-10 of 136 extracted citations

Brain disorders and the biological role of music

Social cognitive and affective neuroscience • 2015
View 4 Excerpts
Highly Influenced

Morphometric and histologic substrates of cingulate integrity in elders with exceptional memory capacity.

The Journal of neuroscience : the official journal of the Society for Neuroscience • 2015
View 4 Excerpts
Highly Influenced

Von Economo neurons : A Review of the Anatomy and Functions

AO Ibegbu
2015
View 5 Excerpts
Highly Influenced

Anterior insular cortex and emotional awareness.

The Journal of comparative neurology • 2013
View 4 Excerpts
Highly Influenced

References

Publications referenced by this paper.
Showing 1-10 of 44 references

Spindle neurons of the human anterior cingulate cortex.

The Journal of comparative neurology • 1995
View 8 Excerpts
Highly Influenced

Human restingstate cortical-subcortical networks for salience processing and executive control

WW Seeley, V Menon, AF Schatzberg
Brain • 2006
View 1 Excerpt

Alz - heimer ’ s disease : cellspecific pathology isolates the hippocampal formation

BT Hyman, AR Damasio, GW VanHoesen, CL Barnes
J Comp Neurol • 2005

Similar Papers

Loading similar papers…