Early expression of endomucin on endothelium of the mouse embryo and on putative hematopoietic clusters in the dorsal aorta.

@article{Brachtendorf2001EarlyEO,
  title={Early expression of endomucin on endothelium of the mouse embryo and on putative hematopoietic clusters in the dorsal aorta.},
  author={Gertrud Brachtendorf and Annegret Kuhn and Ulrike Samulowitz and Ruth Knorr and Erika Gustafsson and Alexandre J. Potocnik and Reinhard F{\"a}ssler and Dietmar Vestweber},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  year={2001},
  volume={222 3},
  pages={410-9}
}
Endomucin is a recently identified sialomucin that is specifically expressed on endothelium of the adult mouse. Here, we have analysed the expression of endomucin during development of the vascular system by immunohistochemistry by using three monoclonal antibodies (mAb). We demonstrate that two of the mAb, V.5C7 and V.1A7, recognize epitopes on the nonglycosylated protein, because they recognize the antigen when it is synthesized as a bacterial fusion protein and when it is in vitro translated… CONTINUE READING
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