Early exposure to ethanol or red wine and long-lasting effects in aged mice. A study on nerve growth factor, brain-derived neurotrophic factor, hepatocyte growth factor, and vascular endothelial growth factor.

@article{Ceccanti2012EarlyET,
  title={Early exposure to ethanol or red wine and long-lasting effects in aged mice. A study on nerve growth factor, brain-derived neurotrophic factor, hepatocyte growth factor, and vascular endothelial growth factor.},
  author={Mauro Ceccanti and Rosanna Mancinelli and Paola Tirassa and Giovanni Laviola and Simona Rossi and Marina Romeo and Marco Fiore},
  journal={Neurobiology of aging},
  year={2012},
  volume={33 2},
  pages={359-67}
}
Prenatal ethanol exposure produces severe changes in brain, liver, and kidney through mechanisms involving growth factors. These molecules regulate survival, differentiation, maintenance, and connectivity of brain, liver, and kidney cells. Despite the abundant available data on the short and mid-lasting effects of ethanol intoxication, only few data show the long-lasting damage induced by early ethanol administration. The aim of this study was to investigate changes in nerve growth factor (NGF… CONTINUE READING
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