Early exposure of 17α-ethynylestradiol and diethylstilbestrol induces morphological changes and alters ovarian steroidogenic pathway enzyme gene expression in catfish, Clarias gariepinus.

@article{Sridevi2015EarlyEO,
  title={Early exposure of 17α-ethynylestradiol and diethylstilbestrol induces morphological changes and alters ovarian steroidogenic pathway enzyme gene expression in catfish, Clarias gariepinus.},
  author={Parikipandla Sridevi and Ratana Chaitanya and Yarikipati Prathibha and Shrilatha Balakrishna and Aparna Dutta-Gupta and Balasubramanian Senthilkumaran},
  journal={Environmental toxicology},
  year={2015},
  volume={30 4},
  pages={439-51}
}
Environmental estrogens are major cause of endocrine disruption in vertebrates, including aquatic organisms. Teleosts are valuable and popular models for studying the effects of endocrine disrupting chemicals (EDCs) in the environment. In the present study, we investigated the changes caused by exposure to the synthetic estrogens 17α-ethynylestradiol (EE2 ) and diethylstilbesterol (DES) during early stages of growth and sex differentiation of air-breathing catfish, Clarias gariepinus, at the… CONTINUE READING
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