Early experience with the ionescu-shiley pericardial xenograft valve. Accelerated calcification in children.

@article{Walker1983EarlyEW,
  title={Early experience with the ionescu-shiley pericardial xenograft valve. Accelerated calcification in children.},
  author={William Ernest Walker and J. Michael Duncan and O. Howard Frazier and James J. Livesay and David A. Ott and George J. Jr. Reul and Denton A. Cooley},
  journal={The Journal of thoracic and cardiovascular surgery},
  year={1983},
  volume={86 4},
  pages={
          570-5
        }
}
Recognizing the problems of thromboembolism and anticoagulation in children and the high incidence of calcification in porcine valves in children, we hoped that the Ionescu-Shiley valve might be a good choice in the younger age group. We implanted 2,372 Ionescu-Shiley valves in 2,167 patients between 1978 and 1982, of which 30 were in children 16 years of age and younger. Although there have been no known instances of thromboembolism, valve infection, or valve disruption in this group of… CONTINUE READING

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