Early experience and serotonin transporter gene variation interact to influence primate CNS function

@article{Bennett2002EarlyEA,
  title={Early experience and serotonin transporter gene variation interact to influence primate CNS function},
  author={Allyson J. Bennett and K. Peter Lesch and Armin Heils and Jeffrey C. Long and Joseph G. Lorenz and Susan Elizabeth Shoaf and Maribeth Champoux and Stephen J. Suomi and Markku Linnoila and James Dee Higley},
  journal={Molecular Psychiatry},
  year={2002},
  volume={7},
  pages={118-122}
}
Nonhuman primates offer unique opportunities to study the effects of genes, environments, and their interaction, on physiology and complex behavior. We examined genotype and early environment contributions to CNS function in a large sample of rhesus monkeys. In humans, length variation of the serotonin (5-HT) transporter (5-HTT) gene-linked polymorphic region (5-HTTLPR) that results in allelic variation in 5-HTT expression is associated with decreased serotonergic function and 5-HT-mediated… CONTINUE READING
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