Early exercise in spinal cord injured rats induces allodynia through TrkB signaling.

  title={Early exercise in spinal cord injured rats induces allodynia through TrkB signaling.},
  author={Teruaki Endo and Takashi Ajiki and Hirokazu Inoue and Motoshi Kikuchi and Takashi Yashiro and Sueo Nakama and Yuichi Hoshino and Takashi Murakami and Eiji Kobayashi},
  journal={Biochemical and biophysical research communications},
  volume={381 3},
Rehabilitation is important for the functional recovery of patients with spinal cord injury. However, neurological events associated with rehabilitation remain unclear. Herein, we investigated neuronal regeneration and exercise following spinal cord injury, and found that assisted stepping exercise of spinal cord injured rats in the inflammatory phase causes allodynia. Sprague-Dawley rats with thoracic spinal cord contusion injury were subjected to assisted stepping exercise 7 days following… CONTINUE READING


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