Early events in the assembly of major histocompatibility complex class II heterotrimers from their free subunits.

Abstract

Endogenous antigen presentation by major histocompatibility complex class II molecules can be understood if class II alpha beta heterodimers bind peptide in the endoplasmic reticulum (ER) before they associate with the invariant chain (Ii). We have studied the assembly of class II molecules from the free alpha, beta and Ii subunits to examine the existence… (More)

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Cite this paper

@article{Nijenhuis1994EarlyEI, title={Early events in the assembly of major histocompatibility complex class II heterotrimers from their free subunits.}, author={Miranda Nijenhuis and Jacques J C Neefjes}, journal={European journal of immunology}, year={1994}, volume={24 1}, pages={247-56} }