Early events in glutamate receptor trafficking.


Glutamate receptors are the primary mediators of excitatory synaptic transmission in the mammalian central nervous system. Activity-dependent changes in the number of postsynaptic glutamate receptors underlie aspects of synaptic plasticity and provide a mechanism for information storage in the brain. Recent work shows that receptor exit from the endoplasmic reticulum represents a critical regulatory step in glutamate receptor trafficking to the neuronal cell surface.

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@article{Vandenberghe2004EarlyEI, title={Early events in glutamate receptor trafficking.}, author={Wim Vandenberghe and David S. Bredt}, journal={Current opinion in cell biology}, year={2004}, volume={16 2}, pages={134-9} }