Early empiric antibiotic use in preterm infants is associated with lower bacterial diversity and higher relative abundance of Enterobacter.

@article{Greenwood2014EarlyEA,
  title={Early empiric antibiotic use in preterm infants is associated with lower bacterial diversity and higher relative abundance of Enterobacter.},
  author={Corryn S Greenwood and A Leslie Morrow and Anne J. Lagomarcino and Mekibib Altaye and Diana H. Taft and Zhuoteng Yu and David S Newburg and Doyle V. Ward and Kurt R. Schibler},
  journal={The Journal of pediatrics},
  year={2014},
  volume={165 1},
  pages={23-9}
}
OBJECTIVES To determine the impact of empiric ampicillin and gentamicin use in the first week of life on microbial colonization and diversity in preterm infants. STUDY DESIGN The 16s ribosomal DNA community profiling was used to compare the microbiota of 74 infants born ≤32 weeks gestational age by degree of antibiotic use in the first week of life. The degree of antibiotic use was classified as 0 days, 1-4 days, and 5-7 days of antibiotic administration. All of the antibiotic use was empiric… CONTINUE READING