Early embryonic induction in C. elegans can be inhibited with polysulfated hydrocarbon dyes.

@article{Bossinger1996EarlyEI,
  title={Early embryonic induction in C. elegans can be inhibited with polysulfated hydrocarbon dyes.},
  author={Olaf Bossinger and Einhard Schierenberg},
  journal={Developmental biology},
  year={1996},
  volume={176 1},
  pages={17-21}
}
During embryogenesis of Caenorhabditis elegans cellular interactions are necessary to determine the fate of blastomeres. In one of these interactions, taking place in the 4-cell stage, the germline cell P2 induces longitudinal orientation of the cleavage spindle in the neighboring EMS cell, its asymmetric division, and the establishment of a gut lineage. Application of several polysulfated hydrocarbon dyes (e.g., trypan blue, TB) in the 1- to 4-cell stages inhibits induction of the gut… CONTINUE READING
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