Early embryo loss is associated with the prior expression of macrophage activation markers in the decidua.

@article{Haddad1997EarlyEL,
  title={Early embryo loss is associated with the prior expression of macrophage activation markers in the decidua.},
  author={Elias K Haddad and Aroune Duclos and Wayne S. Lapp and Malcolm G. Baines},
  journal={Journal of immunology},
  year={1997},
  volume={158 10},
  pages={4886-92}
}
In early embryo loss, the activation of maternal immune effector mechanisms play a critical role in determining the success or failure of a pregnancy. We have previously shown that increased nitric oxide production by decidual macrophages is involved in early embryo loss occurring at day 12 of gestation. In this study, using reverse transcription-PCR and Southern blotting, the expression of inducible nitric oxide synthases (iNOS) and TNF-alpha mRNA was determined to quantify macrophage… CONTINUE READING

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