Early effects of combretastatin A4 phosphate assessed by anatomic and carbogen-based functional magnetic resonance imaging on rat bladder tumors implanted in nude mice.

@article{Thomas2006EarlyEO,
  title={Early effects of combretastatin A4 phosphate assessed by anatomic and carbogen-based functional magnetic resonance imaging on rat bladder tumors implanted in nude mice.},
  author={C D Thomas and Christine Walczak and Julia Kaffy and Ren{\'e}e Pontikis and Jacqueline Jouanneau and Andreas Volk},
  journal={Neoplasia},
  year={2006},
  volume={8 7},
  pages={587-95}
}
Combretastatin A4 phosphate (CA4P) causes rapid disruption of the tumor vasculature and is currently being evaluated for antivascular therapy. We describe the initial results obtained with a noninvasive multiparametric magnetic resonance imaging (MRI) approach to assess the early effects of CA4P on rat bladder tumors implanted on nude mice. MRI (4.7 T… CONTINUE READING