Early drusen formation in the normal and aging eye and their relation to age related maculopathy: a clinicopathological study.

@article{Sarks1999EarlyDF,
  title={Early drusen formation in the normal and aging eye and their relation to age related maculopathy: a clinicopathological study.},
  author={Shirley Sarks and Jennifer J. Arnold and Murray C. Killingsworth and John Sarks},
  journal={The British journal of ophthalmology},
  year={1999},
  volume={83 3},
  pages={358-68}
}
AIM To describe the early formation of drusen and their relation to normal aging changes at the macula and to the development of age related maculopathy (ARM). METHOD Histopathological features of 353 eyes without histological evidence of ARM are described and correlated with the clinical appearance. In addition, 45 of these eyes were examined by transmission electron microscopy. RESULTS Drusen were detected histopathologically in 177 (50%) eyes but were seen clinically in only 34% of these… CONTINUE READING
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