Early diagnosis of zoster sine herpete and antiviral therapy for the treatment of facial palsy

  title={Early diagnosis of zoster sine herpete and antiviral therapy for the treatment of facial palsy},
  author={Y. Furuta and F. Ohtani and Y. Mesuda and S. Fukuda and Y. Inuyama},
  pages={708 - 710}
Article abstract The effect of antiviral agents on recovery from facial palsy in patients with zoster sine herpete (ZSH; varicella zoster virus reactivation without zoster) has not been evaluated because ZSH is difficult to diagnose early after onset. In this study, all 13 patients who received acyclovir-prednisone treatment within 7 days of onset, as confirmed by a positive PCR result, showed complete recovery. PCR-based early diagnosis of ZSH and antiviral therapy elicited an excellent… Expand
Zoster sine herpete causing facial palsy.
The initiation of recovery in ZSH started later than that in other peripheral palsies, and slower recovery was shown in patients with ZSH with pain compared with those with Bell palsy, and Steroid-antiviral combination therapy was a more effective regimen for treatment compared with steroid-only treatment. Expand
Zoster sine herpete: a review
It is shown that the misdiagnosis of ZSH and tardy antiviral treatment may lead to severe ZSH sequelae, and more work about ZSH, especially ZSH epidemiological survey and guidelines for its diagnosis and treatment are needed. Expand
A Case of Associated Laryngeal Paralysis Caused by Varicella Zoster Virus without Eruption
When the authors encounter a patient with associated laryngeal paralysis, the possibility of reactivation of VZV even when no typical herpetic eruption is observed should be considered. Expand
Diagnosis and Treatment of Zoster-Associated Facial Palsy
Most cases of unilateral peripheral facial palsy (Bell's palsy) are idiopathic. However, facial palsy sometimes occurs with reactivation of varicella zoster virus (VZV); in a subset of such cases,Expand
The protean neurologic manifestations of varicella-zoster virus infection.
Multiple neurologic complications may follow the reactivation of varicella-zoster virus (VZV), including herpes zoster (also known as zoster or shingles), postherpetic neuralgia, vasculopathy,Expand
The association of Varicella zoster virus reactivation with Bell's palsy in children.
VZV reactivation may be an important cause of acute peripheral facial paralysis in children and the appropriate diagnosis of VZV reactsivation should be done to improve the outcome and the cure rate by the early use of antiviral treatment. Expand
Reactivation of Herpes Simplex Virus Type 1 and Varicella‐Zoster Virus and Therapeutic Effects of Combination Therapy With Prednisolone and Valacyclovir in Patients With Bell's Palsy
Objectives: To determine whether reactivation of herpes simplex virus (HSV) type 1 or varicella‐zoster virus (VZV) is the main cause of Bell's palsy and whether antiviral drugs bring about recoveryExpand
Valacyclovir for the treatment of Bell's palsy
It is recommended that valacyclovir should be used in cases of severe palsy within 3 days after the onset of Bell's palsy, and the cost–benefit ratio of this treatment and the limitations of virological diagnoses are considered. Expand
Herpes Sine Zoster: Is the Cause for the Segmental Intercostal Neuralgia of Unknown Cause? - A case report-
All the patients were treated for postherpetic neuralgia, resulting in a significant decrease in the intercostal Neuralgia. Expand
A case of zoster sine herpete presenting with thoracic radicular pain diagnosed by polymerase chain reaction in skin exudate
This is believed to be the first case of ZSH diagnosed by using PCR analysis of skin exudate in a patient in whom the cranial nerve was not involved. Expand


Treatment of ramsay hunt syndrome with acyclovir‐prednisone: Significance of early diagnosis and treatment
Early administration of acyclovir‐prednisone was proved to reduce nerve degeneration by nerve excitability testing and hearing recovery also tended to be better in patients with early treatment. Expand
Detection of varicella‐zoster virus DNA in patients with acute peripheral facial palsy by the polymerase chain reaction, and its use for early diagnosis of zoster sine herpete
Results indicate that detection of VZV DNA in oropharyngeal swabs by PCR is more useful than currently available serological assays for the early diagnosis of zoster sine herpete in patients with APFP. Expand
Ramsay Hunt Facial Paralysis: Clinical Analyses of 185 Patients
  • R. Robillard, R. Hilsinger, K. Adour
  • Medicine
  • Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery
  • 1986
The facial palsy of Ramsay Hunt syndrome was found to be more severe, to cause late neural denervation, and to have a less favorable recovery profile than Bell's (herpes simplex) facial palsies. Expand
Idiopathic facial nerve paralysis: A randomized double blind controlled study of placebo versus prednisone
Idiopathic facial nerve paralysis is a common malady and there are a variety of treatment options, but the benefits of treatment with oral steroids (prednisone) are not clearly established. Expand
Bell's Palsy Treatment with Acyclovir and Prednisone Compared with Prednisone Alone: A Double-Blind, Randomized, Controlled Trial
It is concluded that acyclovir-prednisone is superior to prednisone alone in treating Bell's palsy patients and suggest that herpes simplex is the probable cause of Bell’s palsy. Expand
Acute Bell's palsy: prognostic value of evoked electromyography, maximal stimulation, and other electrical tests.
Thirty-seven patients with acute Bell's palsy who had complete unilateral facial paralysis were selected for this study and evoked EMG and the maximal stimulation test agreed in 89 percent of cases in predicting the ultimate outcome of facial paralysis. Expand