Early diagnosis of Parkinson's disease

Abstract

In idiopathic Parkinson's disease (IPD) approximately 60 % of the nigrostriatal neurons of the substantia nigra (SN) are degenerated before neurologists can establish the diagnosis according to the widely accepted clinical diagnostic criteria. It is conceivable that neuroprotective therapy starting at such an ‘advanced stage’ of the disease will fail to… (More)
DOI: 10.1007/s00415-002-1309-9

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Cite this paper

@article{Becker1981EarlyDO, title={Early diagnosis of Parkinson's disease}, author={Georg A. Becker and Antje M{\"{u}ller and Stefan Braune and Thomas B{\"{u}ttner and Reiner Benecke and Wolfgang Greulich and Wolfgang Klein and G{\"{u}nter Mark and J{\"{u}rgen Rieke and Reiner Th{\"{u}mler}, journal={Journal of Neurology}, year={1981}, volume={249}, pages={iii40-iii48} }