Early development of the thymus in Xenopus laevis.

  title={Early development of the thymus in Xenopus laevis.},
  author={Young Hoon Lee and Allison Williams and C S Hong and Youngjae You and Makoto Senoo and Jean-Pierre Saint-Jeannet},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  volume={242 2},
BACKGROUND Although Xenopus laevis has been a model of choice for comparative and developmental studies of the immune system, little is known about organogenesis of the thymus, a primary lymphoid organ in vertebrates. Here we examined the expression of three transcription factors that have been functionally associated with pharyngeal gland development, gcm2, hoxa3, and foxn1, and evaluated the neural crest contribution to thymus development. RESULTS In most species Hoxa3 is expressed in the… CONTINUE READING
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