Early development of the myotome in the mouse.

  title={Early development of the myotome in the mouse.},
  author={Sara J. Venters and S{\'o}lveig Thorsteinsd{\'o}ttir and Marilyn J. Duxson},
  journal={Developmental dynamics : an official publication of the American Association of Anatomists},
  volume={216 3},
The structure and development of the myotome has been extensively studied in birds and amphibians but few studies have systematically addressed its development in mammals. We have used a transgenic mouse carrying an nLacZ marker coupled to a myosin light chain 3F promoter to describe the structure of the developing mammalian myotome. Through studies of transgene expression pattern, coupled with immunohistochemistry for the muscle structural proteins desmin and slow myosin heavy chain we… CONTINUE READING