Early detection of response to hydroxyurea therapy in patients with sickle cell anemia.


Red blood cells (RBC) and reticulocyte parameters were determined on peripheral blood from a subset of patients enrolled in the multicenter study of hydroxyuea (HU) in sickle cell anemia. Multiple blood samples were obtained every 2 weeks. Cellular indices were measured by flow cytometry. Generalized linear models were used to determine the relationship… (More)
DOI: 10.3109/03630269.2010.513638


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