Early detection of liver steatosis by magnetic resonance imaging in rats infused with glucose and intralipid solutions and correlation to insulin levels.

@article{dAssignies2013EarlyDO,
  title={Early detection of liver steatosis by magnetic resonance imaging in rats infused with glucose and intralipid solutions and correlation to insulin levels.},
  author={Gaspard d'Assignies and Ghislaine Font{\'e}s and Claude Kauffmann and Martin G. Latour and Louis Gaboury and Yvan Boulanger and Bernard E. Van Beers and Gilles Soulez and Vincent Poitout and An Tang},
  journal={Metabolism: clinical and experimental},
  year={2013},
  volume={62 12},
  pages={
          1850-7
        }
}
OBJECTIVE Magnetic resonance (MR) techniques allow noninvasive fat quantification. We aimed to investigate the accuracy of MR imaging (MRI), MR spectroscopy (MRS) and histological techniques to detect early-onset liver steatosis in three rat phenotypes assigned to an experimental glucolipotoxic model or a control group. MATERIALS AND METHODS This study was approved by the institutional committee for the protection of animals. Thirty-two rats (13 young Wistar, 6 old Wistar and 13 diabetic Goto… CONTINUE READING

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