Early detection of leprosy by examination of household contacts, determination of serum anti-PGL-1 antibodies and consanguinity.

@article{BazanFurini2011EarlyDO,
  title={Early detection of leprosy by examination of household contacts, determination of serum anti-PGL-1 antibodies and consanguinity.},
  author={Renata Bazan-Furini and Ana Carolina F Motta and Jo{\~a}o Carlos Lopes Sim{\~a}o and Daniela Chaves Tarqu{\'i}nio and Wilson Junior Marques and Marcello Henrique Nogueira Barbosa and Norma Tiraboschi Foss},
  journal={Memorias do Instituto Oswaldo Cruz},
  year={2011},
  volume={106 5},
  pages={536-40}
}
A cross-sectional clinical trial in which the serum anti-phenolic glycolipid (anti-PGL-1) antibodies were analysed in household contacts (HHC) of patients with leprosy as an adjunct early leprosy diagnostic marker was conducted. The families of 83 patients underwent clinical examination and serum anti-PGL1 measurement using enzyme-linked immunosorbent assay. Of 320 HHC, 98 were contacts of lepromatous leprosy (LL), 80 were contacts of borderline lepromatous (BL), 28 were contacts of borderline… CONTINUE READING
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