Early detection and intervention in first‐episode schizophrenia: a critical review

@article{Larsen2001EarlyDA,
  title={Early detection and intervention in first‐episode schizophrenia: a critical review},
  author={T. K. Larsen and Svein Friis and Ulrik Helt Haahr and Inge Joa and Jan Olav Johannessen and Ingrid Melle and Stein Opjordsmoen and Erik Simonsen and Per Wiggen Vaglum},
  journal={Acta Psychiatrica Scandinavica},
  year={2001},
  volume={103}
}
Objective: To review the literature on early intervention in psychosis and to evaluate relevant studies. 
Prospective investigations of the prodromal state of schizophrenia: review of studies
TLDR
A comprehensive overview of prospective studies monitoring or intervening in the pre‐onset phase of first episode psychosis is presented.
One‐year outcome in first episode psychosis patients in the Swedish Parachute project
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Objective:  Implementing a system designed to treat first episode psychotic (FEP) patients by designing a system to diagnose and treat such patients.
Neuropsychological functions predict 1‐ and 3‐year outcome in first‐episode psychosis
TLDR
Examination of neuropsychological performance as a possible predictor of course and outcome in first‐episode psychotic (FEP) patients finds no clear trend in either direction.
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TLDR
The aim of this review was to examine whether interventions in the prodromal phase have a favourable benefit/risk ratio.
Comparison of first‐episode and chronic patients diagnosed with schizophrenia: symptoms and childhood trauma
There has been considerable interest in identifying and addressing the specific needs of early‐episode patients diagnosed with schizophrenia in the hope that by addressing such needs early, chronic
Treatment delay and response rate in first episode psychosis
Objective:  There is no consistent evidence of long duration of untreated psychosis (DUP) predicting long time to response (TTR) in first psychosis. This study aims to investigate the predictors of
Treatment costs and clinical outcome for first episode schizophrenia patients: a 3‐year follow‐up of the Swedish ‘Parachute Project’ and Two Comparison Groups
TLDR
Objective:  To evaluate ‘need‐specific treatment’ of first episode schizophrenia syndrome patients with high need for treatment with antipsychotic medication.
Early detection and treatment of schizophrenia: how early?
TLDR
If and when early detection and therapy of schizophrenic psychoses until some time ago concentrated on frank schizophrenia is justified in the light of recent research is discussed.
The Italian guidelines for early intervention in schizophrenia: development and conclusions
TLDR
The guidelines described in the present paper were aimed at contributing to the current debate by providing Italian practitioners, families, patients and health managers with evidence‐based information on early intervention.
Early detection: a survey of secondary school teachers' knowledge about psychosis
Aims: To establish how much knowledge and experience secondary school‐teachers have about psychosis, sources of help available and how to access help.
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TLDR
It is argued that the first two or three years following a first episode of psychosis is a crucial period for high-quality psychosocial and biological interventions and a time slot which may influence recovery and long-term outcome.
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The duration of untreated psychosis and 12‐month outcome in first‐episode psychosis and the impact of treatment approach are studied.
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