Early cytokine response to multiple injury.

@article{Fox1993EarlyCR,
  title={Early cytokine response to multiple injury.},
  author={B. Fo{\"e}x and W. R. Lamb and T. Roberts and S. Brear and I. Macartney and M. Hammer and P. Brenchley},
  journal={Injury},
  year={1993},
  volume={24 6},
  pages={
          373-6
        }
}
Serial measurements of the inflammatory cytokines interleukin 6 (IL-6) and tumour necrosis factor alpha (TNF alpha) were made in four patients with multiple injuries to characterize secretion patterns and to relate them to severity of injury and degree of haemorrhage. IL-6 and TNF alpha were assayed using a sandwich ELISA. Injury scores varied from 9 to 50, and transfusion requirements varied from 7 to 14 units. All patients showed an increase in IL-6 but only one a rise in TNF alpha. There was… Expand
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