Early clinical experience with integrelin, an inhibitor of the platelet glycoprotein IIb/IIIa integrin receptor.

Abstract

Aggregation of platelets leading to thrombosis is one of the hallmarks of unstable angina, acute myocardial infarction, and ischaemic complications following coronary angioplasty. Activated platelets bind to fibrinogen through the glycoprotein IIb/IIIa integrin receptor. New agents have been developed to bind this receptor and thus prevent aggregation of… (More)

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@article{Ohman1995EarlyCE, title={Early clinical experience with integrelin, an inhibitor of the platelet glycoprotein IIb/IIIa integrin receptor.}, author={E. Magnus Ohman and Robert A. Harrington and Abraham Michael Lincoff and Michael M. Kitt and Neal S. Kleiman and James E. Tcheng}, journal={European heart journal}, year={1995}, volume={16 Suppl L}, pages={50-5} }