Early clinical development of artemether-lumefantrine dispersible tablet: palatability of three flavours and bioavailability in healthy subjects

@inproceedings{Abdulla2010EarlyCD,
  title={Early clinical development of artemether-lumefantrine dispersible tablet: palatability of three flavours and bioavailability in healthy subjects},
  author={Salim Abdulla and Baraka Amuri and Abdunoor M Kabanywanyi and David Ubben and Christine J. Reynolds and Steve Pascoe and Serge Fitoussi and Ching-Ming Yeh and Marja Nuortti and Romain S{\'e}chaud and Guenther Kaiser and Gilbert Y. Lef{\`e}vre},
  booktitle={Malaria Journal},
  year={2010}
}
Efforts to ease administration and enhance acceptability of the oral anti-malarial artemether-lumefantrine (A-L) crushed tablet to infants and children triggered the development of a novel dispersible tablet of A-L. During early development of this new formulation, two studies were performed in healthy subjects, one to evaluate the palatability of three flavours of A-L, and a second one to compare the bioavailability of active principles between the dispersible tablet and the tablet… CONTINUE READING
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