Early childhood cirrhoses (ECC) in Germany between 1982 and 1994 with special consideration of copper etiology.

@article{Dieter1999EarlyCC,
  title={Early childhood cirrhoses (ECC) in Germany between 1982 and 1994 with special consideration of copper etiology.},
  author={Hermann H Dieter and Wolfgang Schimmelpfennig and Elisabeth Meyer and Matthias Tabert},
  journal={European journal of medical research},
  year={1999},
  volume={4 6},
  pages={233-42}
}
In a multicentric retrospective clinical study with 16 pediatric centres we identified 103 cases of histologically confirmed early childhood cirrhosis (ECC) in Germany for the years 1984-1994. The most prominent diagnoses were congenital bile duct anomalies (47.5%), inborn metabolic disorders (17.5%) and unclear etiologies (17.5%). Chronic and excessive intake of copper might be discussed as an etiological factor in 8 other cases. 5 of these were proven to have coincided with very high hepatic… CONTINUE READING