Early changes of intracranial pressure, perfusion pressure, and blood flow after acute head injury. Part 1: An experimental study of the underlying pathophysiology.

@article{Pfenninger1989EarlyCO,
  title={Early changes of intracranial pressure, perfusion pressure, and blood flow after acute head injury. Part 1: An experimental study of the underlying pathophysiology.},
  author={Ernst G. Pfenninger and Albrecht Reith and Dieter Breitig and Adolf Gruenert and Friedrich Wilhelm Ahnefeld},
  journal={Journal of neurosurgery},
  year={1989},
  volume={70 5},
  pages={774-9}
}
The present study examines intracranial pressure (ICP), cerebral perfusion pressure (CPP), and cerebral circulation immediately after experimental head injury in an animal model. The underlying systemic hemodynamic changes were also observed. To produce a standardized head injury, a fluid-percussion device was applied to the dura at the midline of 10 piglets. Seven other nontraumatized animals served as a control group. Hemodynamic parameters as well as ICP and CPP were recorded on-line, one… CONTINUE READING

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