Early changes in rat hearts with developing pulmonary arterial hypertension can be detected with three-dimensional electrocardiography.

@article{Henkens2007EarlyCI,
  title={Early changes in rat hearts with developing pulmonary arterial hypertension can be detected with three-dimensional electrocardiography.},
  author={Ivo R Henkens and Koen T. B. Mouchaers and Hubert W. Vliegen and Willem J van der Laarse and Cees A. Swenne and Arie C. Maan and Harmen H. M. Draisma and Ingrid Schalij and E. E. van der Wall and Martin Jan Schalij and Anton Vonk-Noordegraaf},
  journal={American journal of physiology. Heart and circulatory physiology},
  year={2007},
  volume={293 2},
  pages={H1300-7}
}
The study aim was to assess three-dimensional electrocardiogram (ECG) changes during development of pulmonary arterial hypertension (PAH). PAH was induced in male Wistar rats (n = 23) using monocrotaline (MCT; 40 mg/kg sc). Untreated healthy rats served as controls (n = 5). ECGs were recorded with an orthogonal three-lead system on days 0, 14, and 25 and analyzed with dedicated computer software. In addition, left ventricular (LV)-to-right ventricular (RV) fractional shortening ratio was… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 20 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 34 references

Immunohistochemical determination of cytosolic cytochrome C concentration in cardiomyocytes

  • BJ Beek-Harmsen, WJ vanderLaarse
  • J Histochem Cytochem
  • 2005
1 Excerpt

Similar Papers

Loading similar papers…