Early brain changes associated with psychotherapy in major depressive disorder revealed by resting-state fMRI: evidence for the top-down regulation theory.

@article{Huang2014EarlyBC,
  title={Early brain changes associated with psychotherapy in major depressive disorder revealed by resting-state fMRI: evidence for the top-down regulation theory.},
  author={Xiaolan Huang and Peiyu Huang and Dan Li and Yong Zhang and Tao Wang and Jun Mu and Qi Li and Peng Hui Xie},
  journal={International journal of psychophysiology : official journal of the International Organization of Psychophysiology},
  year={2014},
  volume={94 3},
  pages={437-44}
}
BACKGROUND Major depressive disorder (MDD) is associated with dysfunction of the emotional circuitry in the brain. Psychotherapy and antidepressant treatment both aid in modulating this dysfunction, albeit probably through different mechanisms. A plausible "top-down" emotional regulation mechanism for psychotherapy has been described in previous studies, but the underlying findings are still contradictory. METHODS A total of 23 MDD patients and 20 healthy controls were enrolled. The early… CONTINUE READING
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