Early botulinum toxin treatment for spastic pes equinovarus--a randomized double-blind placebo-controlled study.

@article{Fietzek2014EarlyBT,
  title={Early botulinum toxin treatment for spastic pes equinovarus--a randomized double-blind placebo-controlled study.},
  author={Urban M. Fietzek and Peter Kossmehl and Ludwig D. Schelosky and Georg Ebersbach and Joerg Wissel},
  journal={European journal of neurology},
  year={2014},
  volume={21 8},
  pages={1089-1095}
}
BACKGROUND AND PURPOSE Spastic pes equinovarus is a frequent pathological posture of the lower extremity. Botulinum toxin (BoNT/A) has been successfully applied to treat lower limb spasticity. However, the best time to initiate treatment remains unclear. A beneficial effect of an early treatment has been suggested in previous studies. METHODS A single-centre double-blind randomized placebo-controlled trial was performed to investigate the efficacy of BoNT/A to reduce muscle hypertonicity at… CONTINUE READING
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