Early biomarkers of stroke.

  title={Early biomarkers of stroke.},
  author={Mark Alexander Reynolds and Howard J Kirchick and Jeffrey R Dahlen and Joseph M Anderberg and Paul H McPherson and Kevin K Nakamura and Daniel T Laskowitz and Gunars E. Valkirs and Kenneth F Buechler},
  journal={Clinical chemistry},
  volume={49 10},
BACKGROUND The diagnosis and management of acute ischemic stroke are limited by the lack of rapid diagnostic assays for use in an emergency setting. Computed tomography (CT) scanning is used to diagnose hemorrhagic stroke but is relatively ineffective (<33% sensitive) in detecting ischemic stroke. The ability to correlate blood-borne protein biomarkers with stroke phenotypes would aid in the development of such rapid tests. METHODS ELISAs for >50 protein biomarkers were developed for use on a… CONTINUE READING
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