Early autologous stem-cell transplantation versus conventional chemotherapy as front-line therapy in high-risk, aggressive non-Hodgkin's lymphoma: an Italian multicenter randomized trial.

Abstract

PURPOSE To evaluate the role of early intensification with high-dose therapy (HDT) and autologous stem-cell transplantation (ASCT) as front-line chemotherapy for patients with high-risk, histologically aggressive non-Hodgkin's lymphoma (NHL). PATIENTS AND METHODS We planned a multicenter, randomized trial to compare a conventional chemotherapy regimen of… (More)

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@article{Martelli2003EarlyAS, title={Early autologous stem-cell transplantation versus conventional chemotherapy as front-line therapy in high-risk, aggressive non-Hodgkin's lymphoma: an Italian multicenter randomized trial.}, author={Maurizio Martelli and Filippo Gherlinzoni and Amalia De Renzo and Pier Luigi Zinzani and Antonio de Vivo and Maria Cantonetti and Brunangelo Falini and Sergio Storti and G. Meloni and Manuela Rizzo and Anna Lia Molinari and Francesco Nicola Lauria and Luciano Moretti and Vito Michele Lauta and Patrizio Mazza and Luciano Guardigni and Edoardo Pescarmona and Stefano A Pileri and Franco Mandelli and Sante Tura}, journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology}, year={2003}, volume={21 7}, pages={1255-62} }