Early asthma prophylaxis, natural history, skeletal development and economy (EASE): a pilot randomised controlled trial.

@article{BaxterJones2000EarlyAP,
  title={Early asthma prophylaxis, natural history, skeletal development and economy (EASE): a pilot randomised controlled trial.},
  author={Adam D G Baxter-Jones and Peter J. Helms and Greg Russell and Amy L Grant and Stephanie H K Ross and John Cairns and Lewis Ritchie and Rod Taylor and Diane Myles Reid and Liesl M Osman and Simon Robins and Mary E Fletcher},
  journal={Health technology assessment},
  year={2000},
  volume={4 28},
  pages={1-89}
}
OBJECTIVES (1) To establish recruitment rates of newly presenting asthmatic children. (2) To establish acceptability of study protocols. (3) To pilot age-specific quality of life (QoL) assessment. (4) To assess short-term (6 months) outcomes of inhaled corticosteroids (ICS) treatment. (5) To refine sample size calculations for a definitive study. DESIGN A randomised pragmatic longitudinal trial design was used, with no blinding or placebo, to examine early ICS introduction similar to its use… CONTINUE READING

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