Early antagonism of cerebral high mobility group box-1 protein is benefit for sepsis induced brain injury


Sepsis induced brain injury acts as an acute complication and accounts for deterioration and high mortality rate of septic condition. HMGB1 is a late inflammatory mediator that plays a critical role in brain dysfunction and diseases. However, the role of HMGB1 in sepsis induced brain dysfunction remains intricate. The current study investigated the effect… (More)
DOI: 10.18632/oncotarget.21502

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