Early and late forms of cyclosporine nephrotoxicity: studies in cardiac transplant recipients.

@article{Greenberg1987EarlyAL,
  title={Early and late forms of cyclosporine nephrotoxicity: studies in cardiac transplant recipients.},
  author={Allison L. Greenberg and J W Egel and Mollie E. Thompson and Robert L. Hardesty and Bartley P. Griffith and Henry T. Bahnson and Robert L. Bernstein and Andrea Hastillo and Michael L. Hess and JulesB. Puschett},
  journal={American journal of kidney diseases : the official journal of the National Kidney Foundation},
  year={1987},
  volume={9 1},
  pages={
          12-22
        }
}
To characterize the two forms of cyclosporine nephrotoxicity, we examined renal function in the immediate and late postoperative periods after cardiac transplantation. Moderate azotemia occurred during the first postoperative week in 58% of 43 cyclosporine-treated recipients, but in only 34% of 41 azathioprine-treated recipients, and 4% of 25 patients undergoing cardiopulmonary bypass for nontransplant surgery (both P less than .01 v cyclosporine). Acute renal failure developed in an additional… CONTINUE READING
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