Early and late failure of noninvasive ventilation in chronic obstructive pulmonary disease with acute exacerbation.

@article{Carrat2005EarlyAL,
  title={Early and late failure of noninvasive ventilation in chronic obstructive pulmonary disease with acute exacerbation.},
  author={Pierluigi Carrat{\'u} and P G Bonfitto and Silvano Dragonieri and Federico Schettini and Roque Clemente and Giuseppe Di Gioia and L Loponte and Maria Pia Foschino Barbaro and Onofrio Resta},
  journal={European journal of clinical investigation},
  year={2005},
  volume={35 6},
  pages={404-9}
}
BACKGROUND Despite recent encouraging results, the use of noninvasive ventilation (NIV) in the management of acute exacerbations in chronic obstructive pulmonary disease (COPD), complicated by acute respiratory failure (ARF), is not always successful. Failure of NIV may require an immediate intubation after a few hours (usually 1-3) of ventilation ('early failure') or may result in clinical deterioration (one or more days later) after an initial improvement of blood gas tension and general… CONTINUE READING
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