Early and late endosomal compartments of Entamoeba histolytica are enriched in cysteine proteases, acid phosphatase and several Ras-related Rab GTPases.

@article{Temesvari1999EarlyAL,
  title={Early and late endosomal compartments of Entamoeba histolytica are enriched in cysteine proteases, acid phosphatase and several Ras-related Rab GTPases.},
  author={Lesly A. Temesvari and Edward N Harris and Samuel L. Stanley and James A. Cardelli},
  journal={Molecular and biochemical parasitology},
  year={1999},
  volume={103 2},
  pages={225-41}
}
Pure populations of early and late endosomes of Entamoeba histolytica were isolated by magnetic fractionation and characterized. It was shown that these vesicles were enriched in acid phosphatase and cysteine protease activities. An important virulence factor, a 27-kDa cysteine protease, was also enriched in early and late endosomes of E. histolytica. These data suggest that E. histolytica hydrolases reside in compartments that are part of or communicate with the endosomal pathway. To begin to… CONTINUE READING

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Role of the Entamoeba histolytica cysteine proteinase in amebic liver abscess formation in severe combined immunodeficient mice

  • SL JrStanley, T Zhang, D Rubin, E. Li
  • Infect Immun
  • 1995
Highly Influential
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