Early amniocentesis at 11-14 weeks' gestation for the diagnosis of fetal chromosomal abnormality--a clinical evaluation.

@article{Hackett1991EarlyAA,
  title={Early amniocentesis at 11-14 weeks' gestation for the diagnosis of fetal chromosomal abnormality--a clinical evaluation.},
  author={Gerald A Hackett and Jonathan Harvey Smith and Mike Rebello and C. Thomas Gray and D E Rooney and Richard William Beard and Frank E L{\"o}ffler and Dulcie V. Coleman},
  journal={Prenatal diagnosis},
  year={1991},
  volume={11 5},
  pages={311-5}
}
Early amniocentesis between 11 and 14 weeks' gestation was offered to 110 women at risk of a chromosomally abnormal fetus due to maternal age. Four were found to be unsuitable for the procedure, and 106 early amniocenteses were performed. In 102 cases, clear amniotic fluid was obtained with a single tap. There were two dry taps and two bloodstained taps; sampling was repeated in three of these cases before 15 weeks. In the fourth case, placental biopsy was performed at 16 weeks. Thus, we were… CONTINUE READING