Early aggressive use of fresh frozen plasma does not improve outcome in critically injured trauma patients.

@article{Scalea2008EarlyAU,
  title={Early aggressive use of fresh frozen plasma does not improve outcome in critically injured trauma patients.},
  author={Thomas M. Scalea and Kelly M. Bochicchio and Kim Lumpkins and John R Hess and Richard B Dutton and Anne Pyle and Grant V. Bochicchio},
  journal={Annals of surgery},
  year={2008},
  volume={248 4},
  pages={578-84}
}
OBJECTIVES Recent data from Iraq supporting early aggressive use of fresh frozen plasma (FFP) in a 1:1 ratio to packed red blood cells (PRBCs) has led many civilian trauma centers to adopt this resource intensive strategy. METHODS Prospective data were collected on 806 consecutive trauma patients admitted to the intensive care unit over 2 years. Patients were stratified by PRBC:FFP transfusion ratio over the first 24 hours. Stepwise regression models were performed controlling for age, gender… CONTINUE READING

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Transfusion: management of blood and blood products in trauma

  • L. Napolitano
  • Asesio JA, Trunkey DD, eds. Current Therapy of…
  • 2008
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